Dynamic axial compression column of high pressure DAC in hisep
Quiksep medium and high pressure organic solvent resistant dynamic axial compression column has the advantages of low cost and reliable performance.
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1. The hydraulic cylinder maintains a constant pressure in the column as required by the process. The air driven hydraulic pump supplies the cylinder with the axial moving power, and can supplement the reduced pressure due to the collapse of the column bed at any time. At the same time, overpressure relief valve is set to adjust overpressure caused by indoor temperature.

2. The column pipe is 316L stainless steel

Column material

Material in contact with mobile phase SS316L

Column height

300-800mm  

Roughness of inner wall of column

Ra < 0.4

3、Distribution of liquid flow between piston and bottom of cylinder

The piston part is composed of hydraulic cylinder connector, sliding pair, piston body, upper and lower guide sleeve, high pressure seal ring, distributor orifice plate, sieve plate and liquid inlet pipe.


The material of piston body is 316L, the material of upper and lower guide sleeve is F4, the material of high-pressure seal ring is PTFE, the material of distributor orifice plate, preparation sieve plate and liquid inlet pipe is 316L.

The relatively important part is the piston distributor. It directly affects the column efficiency.


The piston distributor uses the patented technology "dynamic axial compression column fluid distribution device", and the second derivative calculation method is used to carve the h-tree distribution model on the piston body. Polytetrafluoroethylene is used as the transition plate to realize the secondary distribution. The h-tree distributor is refined to more than eight levels, so that the liquid entering each cross-section of the piston is still on the same cross-section when it reaches the surface of the piston sieve plate, avoiding the sample diffusion in the solvent, so as to ensure the column efficiency of the prepared column..

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Purchased by a pharmaceutical enterprise in Shandong in 2017

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